袁文杰，博士，教授，博士生导师，曾任生物工程学院副院长。研究方向为合成生物学与生物催化转化。致力于解析生物制造过程中微生物及酶的生理特性和催化机制，发展强化微生物生产性能的新技术和新方法，创建新一代工业菌株和酶制剂，提升生物加工过程的效率，实现生物技术产品的智造。主要研究内容包括：(1)新一代工业生产菌株改造与创制；(2)新型生物催化剂设计与催化过程创建。研究的目标集中在生物能源及生物医药产品。取得的研究结果已在Chem Eng J、Green Chem、Bioresour Technol、Fuel、J Biol Chem等国内外期刊发表论文80余篇，授权国内外专利20余项，获辽宁省科技进步奖一等奖、辽宁省自然科学成果一等奖，教育部科技进步二等奖、日内瓦专利金奖、生物工程学报优秀论文奖等多项。承担国家自然科学基金、新疆工信厅揭榜挂帅、国家重点研发项目、863项目、国际合作项目、企业委托项目等二十余项，完成产业化项目2项。

近五年代表性论文：

(1) Zhanyu Jing, Cong Du, Chengpeng Jin,Jirui Wang, Yicen Li, Yimin Li^*, Wenjie Yuan^*. Multifaceted engineering of acyl transferase with a combinatorial hierarchical strategy for dipeptide production. Chemical Engineering Journal, 2026,543:178495.

(2) Cong Du, LiMing Su, RuoKe Yuan, Ying He, Yimin Li^*, Wenjie Yuan^* and FengWu Bai. Integrated bioprocessing of spent yeast for the co-production of high-value flavor nucleotides and functional polysaccharides. Food Chemistry, 2026,522:150070

(3) Ying He, Yimin Li, Jiaxin Liu, Liming Su, Cong Du ^* and Wenjie Yuan^*. The synergistic effect of formate dehydrogenase and carbonic anhydrase accelerates the ethanol fermentation process and improves carbon recovery. Green Chemistry, 2025, 27 (23): 6776-6786.

(4) Cong Du, Ying He, Jiaxin Liu, Liming Su, Yimin Li*, Wenjie Yuan*, Fengwu Bai. Metabolic coupling of acetate promotes xylose utilization in Kluyveromyces marxianus. Chemical Engineering Journal, 2024,484:149762.

(5) Yimin Li, Cong Du, Zhanyu Jing, Jie Zhu, Chao Fan, Yu Jiang, and Wenjie Yuan*. Clean production of L‐Alanyl‐L‐glutamine by an efficient yeast biocatalyst expressing α‐amino acid ester ccyltransferase without N‐glycosylation. Journal of Agriculture Food Chemistry, 2023, 71:6398-6405.

(6) Zhanyu Jing, Jian Xu, Jia Liu, Cong Du, Jiakun Qi, Chao Fan, Yimin Li*, Wenjie Yuan*. Multiplex gene knockout raises Ala‐Gln production by Escherichia coli expressing amino acid ester acyltransferase. Applied Microbiology and Biotechnology, 2023, 107:3523-3533.

(7) Cong Du, Yimin Li, Ying He, Liming Su, Huanan Wang, Wenjie Yuan* and Fengwu Bai. Fixing carbon dioxide in situ during ethanol production by formate dehydrogenase. Green Chemistry, 2022, 24, 6989.

(8) Cong Du, Yimin Li, Ruijuan Xiang, Ying He, Hao Sun, Huanan Wang, Wenjie Yuan*. Co-utilization of multiple lignocellulose-derived sugars and inhibitors by the robust mutant Kluyveromyces marxianus through adaptive laboratory evolution. Fuel, 2022, 315:122816.

(9) Cong Du, Yimin Li, Han Zong, Tangguo Yuan, Wenjie Yuan^⁎, Yu Jiang. Production of bioethanol and xylitol from non-detoxified corn cob via a two-stage fermentation strategy. Bioresource Technology, 2020, 310:123427.