|
个人信息Personal Information
教授
博士生导师
硕士生导师
性别：女
毕业院校：大连理工大学
学位：博士
所在单位：生物工程学院
学科：生物化工. 生物工程与技术. 药物工程
办公地点：生物楼512
联系方式：wangjingyun67@dlut.edu.cn
电子邮箱：wangjingyun67@dlut.edu.cn
Construction of Long-Wavelength Fluorescein Analogues and Their Application as Fluorescent Probes
点击次数：
论文类型：期刊论文
发表时间：2013-05-01
发表刊物：CHEMISTRY-A EUROPEAN JOURNAL
收录刊物：SCIE、EI、PubMed、Scopus
卷号：19
期号：21
页面范围：6538-6545
ISSN号：0947-6539
关键字：colorimetric analysis; fluorescence; fluorescent probes; mitochondria; thiol probes; imaging
摘要：Born to dye: Five fluorescein analogues were synthesised (see scheme). One analogue was found to emit in the NIR region with a high quantum yield, excellent photostability and good permeability. Three derivatives were found to specifically stain mitochondria and one dye responds to thiols with a strong turn-on NIR fluorescence signal and colorimetric change, in vitro and in vivo.Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.