Release Time:2019-03-10  Hits:

Indexed by: Journal Article

Date of Publication: 2008-01-01

Journal: SYNTHETIC COMMUNICATIONS

Included Journals: SCIE

Volume: 38

Issue: 12

Page Number: 1888-1895

ISSN: 0039-7911

Key Words: fluorene bromide derivatives; oxidative bromination; spirobifluorene bromide derivatives

Abstract: A mild, simple, and efficient synthetic procedure for the preparation of 2-monobromo-, 2,7-dibromo-, and 2,2',7,7'-tetrabromo-substituted spirobifluorene derivatives and their key intermediates, 2-monobromo- and 2,7-dibromo-substituted fluorene compounds, has been developed. The oxidative bromination of fluorene and spirobifluorene was achieved using NaBr/H(2)O(2) as the bromine source. High conversion of the starting materials was achieved together with good selectivities under optimized reaction conditions.