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Indexed by:期刊论文

Date of Publication:2008-01-01

Journal:SYNTHETIC COMMUNICATIONS

Included Journals:SCIE

Volume:38

Issue:12

Page Number:1888-1895

ISSN No.:0039-7911

Key Words:fluorene bromide derivatives; oxidative bromination; spirobifluorene bromide derivatives

Abstract:A mild, simple, and efficient synthetic procedure for the preparation of 2-monobromo-, 2,7-dibromo-, and 2,2',7,7'-tetrabromo-substituted spirobifluorene derivatives and their key intermediates, 2-monobromo- and 2,7-dibromo-substituted fluorene compounds, has been developed. The oxidative bromination of fluorene and spirobifluorene was achieved using NaBr/H(2)O(2) as the bromine source. High conversion of the starting materials was achieved together with good selectivities under optimized reaction conditions.