Release Time:2019-03-13  Hits:

Indexed by: Journal Article

Date of Publication: 2016-06-15

Journal: TETRAHEDRON LETTERS

Included Journals: Scopus、SCIE

Volume: 57

Issue: 24

Page Number: 2633-2637

ISSN: 0040-4039

Key Words: Metal-free; alpha/beta-Unsaturated carbonyl compounds; Sulfonyl hydrazides; Iodine catalysis; Pyrazoles

Abstract: A facile and expeditious method for the synthesis of 1H-pyrazoles by the reaction of alpha,beta-unsaturated aldehydes/ketones and sulfonyl hydrazide catalyzed by as low as 2 mol % I-2 has been demonstrated. This synthetic system features simple operation and mild reaction conditions, and displays a broad functional group tolerance furnishing good to excellent yields. (C) 2016 Elsevier Ltd. All rights reserved.