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Indexed by:期刊论文

Date of Publication:2016-06-15

Journal:TETRAHEDRON LETTERS

Included Journals:SCIE、Scopus

Volume:57

Issue:24

Page Number:2633-2637

ISSN No.:0040-4039

Key Words:Metal-free; alpha/beta-Unsaturated carbonyl compounds; Sulfonyl hydrazides; Iodine catalysis; Pyrazoles

Abstract:A facile and expeditious method for the synthesis of 1H-pyrazoles by the reaction of alpha,beta-unsaturated aldehydes/ketones and sulfonyl hydrazide catalyzed by as low as 2 mol % I-2 has been demonstrated. This synthetic system features simple operation and mild reaction conditions, and displays a broad functional group tolerance furnishing good to excellent yields. (C) 2016 Elsevier Ltd. All rights reserved.