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Indexed by:会议论文

Date of Publication:2006-06-21

Included Journals:EI、CPCI-S、Scopus

Volume:2

Page Number:8383-+

Key Words:capillary electrophoresis chips; microfluidic chips; biochips; mu-TAS; hot embossing; numerical simulation

Abstract:A polymer capillary electrophoresis chip is a novel kind of miniaturized device for biochemistry analysis. In this paper, a polymer micro hot embossing process is characterized by experiment and numerical simulation. a series of experiments were carried out with varied process conditions, including processing pressure, temperature and time. both the height and width of hot-embossed microchannel was investigated. Furthermore, a numerical simulation was developed to understand the mechanism of the hot-embossing process. Simulation results conform to related experiments. Based on these, a novel process of hot embossing is proposed, which lays the foundation for basic theories and techniques of structural design and manufactures of the polymer microchip.