location: Current position: Home >> Scientific Research >> Paper Publications

Substrate-controlled divergent synthesis of polycyclic indoloazepines and indolodiazepines via 1,5-hydride shift/7-cyclization cascades

Hits:

Indexed by:期刊论文

Date of Publication:2018-07-21

Journal:CHEMICAL COMMUNICATIONS

Included Journals:SCIE

Volume:54

Issue:57

Page Number:7928-7931

ISSN No.:1359-7345

Abstract:Novel and practical acid-catalyzed cyclization of 2-indolyl aryl carbinols via tandem dehydration/1,5-hydride shift/7-cyclization sequences has been developed. By appropriate variation of the substrate, diverse polycyclic-fused indoles were synthesized in good yield, thus demonstrating the high efficiency, transition-metal-free nature, and high step/atom economy of the synthesis strategy.

Pre One:Highly beta(Z)-Selective Hydrosilylation of Terminal Alkynes Catalyzed by Thiolate-Bridged Dirhodium Complexes

Next One:Construction of indolenine-substituted spiro[pyrrolidine-2,3 '-oxindoles] from 2-alkenylindolenines and isatin-derived azomethine ylides