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Indexed by:期刊论文

Date of Publication:2018-05-10

Journal:TETRAHEDRON

Included Journals:SCIE

Volume:74

Issue:19

Page Number:2369-2375

ISSN No.:0040-4020

Key Words:Spirooxindole; Indolenine; 1,3-Dipolar cycloaddition; Azomethine ylide; Regioselectivity

Abstract:An organic base-catalyzed 1,3-dipolar cycloaddition between 2-alkenylindolenines and azomethine ylides derived from isatins and benzylamines was successfully developed to assemble indolenine-substituted spiro [pyrrolidine-2,3'-oxindole] ring systems. Generally, good regioselectivities (up to 14:1 rr) and high yields (up to 91%) were obtained under mild conditions. (C) 2018 Elsevier Ltd. All rights reserved.