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Indexed by:期刊论文

Date of Publication:2018-03-21

Journal:CHEMCATCHEM

Included Journals:SCIE、EI

Volume:10

Issue:6

Page Number:1248-1252

ISSN No.:1867-3880

Key Words:asymmetric catalysis; heterocycles; heterogeneous catalysis; nanostructures; supported catalysts

Abstract:Porous carbon nanosheets (PCNs) were used for the first time as a support to immobilize a quinine-squaramide catalyst for the asymmetric Friedel-Crafts addition of pyrazolones to isatin ketimines. Relying on its open structure with a macroporous network as well as hydrophobicity, the PCN-supported catalyst presented catalytic performance comparable to its homogeneous catalyst; the products were obtained in high yields (up to 90%) with high ee values (up to 99%). Recycling batch reactions together with a continuous flow process confirmed the stability of the catalyst.