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Indexed by:期刊论文
Date of Publication:2017-04-21
Journal:JOURNAL OF ORGANIC CHEMISTRY
Included Journals:EI、PubMed、SCIE
Volume:82
Issue:8
Page Number:4317-4327
ISSN No.:0022-3263
Abstract:A novel one-pot 1,3-dipolar cycloaddition of indolenines, 3-aminooxindoles, and aldehydes is reported. The reaction provides indolenine-substituted spiro [pyrrolidin-2,3 '-oxindoles] containing four contiguous stereogenic centers in high yields (up to 99%) and excellent diastereoselectivities (up to > 20:1 dr) under mild conditions. Remarkably, the inversion of diastereoselectivity could be readily achieved through slightly modifying the reaction conditions.
Pre One:C-H Activation of Cp* Ligand Coordinated to Ruthenium Center: Synthesis and Reactivity of a Thiolate-Bridged Diruthenium Complex Featuring Fulvene-like Cp* Ligand
Next One:Asymmetric [3+2] Cycloaddition of 3-Amino Oxindole-Based Azomethine Ylides and alpha,beta-Enones with Divergent Diastereocontrol on the Spiro[pyrrolidine-oxindoles]
