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Indexed by:期刊论文
Date of Publication:2012-06-01
Journal:ORGANIC LETTERS
Included Journals:SCIE、PubMed、Scopus
Volume:14
Issue:11
Page Number:2734-2737
ISSN No.:1523-7060
Abstract:The first highly enantio- and diastereoselective vinylogous aldol reaction between propionyl acetate-derived Brassard's diene and aldehydes was accomplished by titanium lithium combined Lewis acid, affording delta-hydroxy-gamma-methyl-beta-methoxy acrylates. This methodology was utilized in convenient and concise construction of the polypropionate moiety in cystothiazole A and mellthiazole C.
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