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Polybrominated diphenylethers (PBDEs) and their hydroxylated metabolites (OH-PBDEs) in female serum from Dalian, China

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Indexed by:期刊论文

Date of Publication:2016-11-01

Journal:INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Included Journals:SCIE、PubMed、Scopus

Volume:219

Issue:8

Page Number:816-822

ISSN No.:1438-4639

Key Words:Polybrominated diphenyl ethers (PBDEs); Hydroxylated metabolites (OH-PBDEs); Female serum; Dalian

Abstract:Seven polybrominated diphenyl ethers (PBDEs) and eleven hydroxylated PBDEs (OH-PBDEs) were selected to investigate their contamination status in 32 female serum samples from Dalian, China. These studied PBDEs and OH-PBDEs were found in most of the serum samples with the concentrations of Sigma PBDEs and Sigma OH-PBDEs ranging from 1.07 to 38.7 ngig lipid (median: 5.56 ng/g lipid) and from 0.011 to 0.436 ng/g lipid (median: 0.069 ng/g lipid), respectively. More impressively, BDE-47 and OH-BDE-47 were the predominant congeners in female serum, accounting for 52% of Sigma PBDEs and 46% of Sigma OH-PBDEs, respectively. Correspondence analysis indicated that significant (p < 0.05) positive correlations were observed between BDE-47 and its metabolites such as 6-OH-BDE-47, 3-0H-BDE-47 and 4'-OH-BDE-49. In addition, the positive significant (p < 0.05) correlation was shown between Sigma PBDEs and lipid contents but between concentrations of Sigma PBDEs and ages or BMIs, as well as for Sigma OH-PBDEs. (C) 2016 Elsevier GmbH. All rights reserved.

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