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论文类型：期刊论文

发表时间：2014-08-01

发表刊物：JOURNAL OF COMPUTATIONAL AND THEORETICAL NANOSCIENCE

收录刊物：SCIE、EI、Scopus

卷号：11

期号：8

页面范围：1745-1749

ISSN号：1546-1955

关键字：Digital Signal; Sequence Representation; Beta-Globin Gene; Cross Correlation Function; Phylogenetic Tree

摘要：The comparison of DNA sequences has been a hot spot in the field of bioinformatics for a long time. Based on digital signal method, we outline a new representation of DNA sequences. Our method provides a transformation from the original sequence to its mathematical representation without loss of information. We take the first exon of beta- globin gene of 13 different species as samples to test our method. Afterwards, we show the distance matrix of the 13 species and illustrate the utility of this scheme by contrasting our result with what other papers have reported before. It is proved that our method is effective and reasonable to measure the similarity/ dissimilarity of different species.