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论文类型： 期刊论文

发表时间： 2018-06-15

发表刊物： SENSORS AND ACTUATORS B-CHEMICAL

收录刊物： SCIE、EI

卷号： 263

页面范围： 661-667

ISSN号： 0925-4005

关键字： Artificial fluorescent protein; Fluorescent recognition; Relay sensing; Silver ion; Nanosensor

摘要： Green fluorescent protein (GFP) becomes one of the most important imaging tools in biology and biomedicine. To simplify usage, expand the application and avoid complicated operations, a kind of artificial fluorescent protein (AFP) is inspired and fabricated by lighting up human serum albumin (HSA) with loading microenvironment-sensitive fluorescent dye DMAR, which could be applied in HSA assay in human urine and serum samples as a physiological indicator of diagnosis in clinical. Besides, the AFP, DMAR/HSA, could act as a nanosensor for Ag+ sensing with good selectivity by a new relay recognition strategy. (C) 2018 Elsevier B.V. All rights reserved.