Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2015-04-01

Journal: SYNLETT

Included Journals: Scopus、SCIE

Volume: 26

Issue: 7

Page Number: 921-926

ISSN: 0936-5214

Key Words: alkaloids; spiroketals; natural products; total synthesis; microwave-assisted reaction

Abstract: Pollenopyrroside A and capparisine B, two diastereoisomers of pyrrole spiroketal alkaloids isolated from Brassica campestris pollen and Capparis spinosa, were synthesized by an improved microwave-assisted bishydroxymethylation of pyrrole and acid-catalyzed spirocyclization as key steps with total yields of 2.7 and 8.8%, respectively.