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Indexed by:期刊论文

Date of Publication:2015-04-01

Journal:SYNLETT

Included Journals:SCIE、Scopus

Volume:26

Issue:7

Page Number:921-926

ISSN No.:0936-5214

Key Words:alkaloids; spiroketals; natural products; total synthesis; microwave-assisted reaction

Abstract:Pollenopyrroside A and capparisine B, two diastereoisomers of pyrrole spiroketal alkaloids isolated from Brassica campestris pollen and Capparis spinosa, were synthesized by an improved microwave-assisted bishydroxymethylation of pyrrole and acid-catalyzed spirocyclization as key steps with total yields of 2.7 and 8.8%, respectively.