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Scientific Research
郭修晗
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Associate Professor Supervisor of Master's Candidates
Scientific Research
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Paper Publications
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Wang Shisheng.Tang, Ze-Yao,Zhang, Qiao-Li,Chu, Peng,Kong, Ling-Qi,李广哲,李悦青,李杨,赵伟杰,郭修晗.Synthesis and antitumor activity of alpha,beta-unsaturated carbonyl moiety-containing oleanolic acid derivatives targeting PI3K/AKT/mTOR signaling pathway[J],BIOORGANIC CHEMISTRY,2022,101
Wang Shisheng.张巧丽,初鹏,李广哲,李悦青,杨丽,赵伟杰,郭修晗.Synthesis and antitumor activity of α,β-unsaturated carbonyl moietycontaining oleanolic acid derivatives targeting PI3K/AKT/mTOR signaling[J],BIOORGANIC CHEMISTRY,2022,101
郭修晗.Yu, Haoze,Shen, Wanjie,蔡蕊,李悦青,李广哲,赵伟杰,Wang Shisheng.Synthesis and biological evaluation of NO-donor containing photosensitizers to induce ferroptosis of cancer cells[J],BIOORGANIC CHEMISTRY,2022,116
Guo, Xiuhan.Wang, SS (reprint author), Dalian Univ Technol, State Key Lab Fine Chem, Sch Pharmaceut Sci & Technol, Dalian 116024, Peoples R China..Wang, Shisheng,Li, Yueqing,Zhang, Fan,Song, Bo,Zhao, Weijie,Wang, Liu.Syntheses of new chlorin derivatives containing maleimide functional group and their photodynamic activity evaluation[J],BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2015,25(19):4078-4081
Cao, Zhi.Zhao, WJ (reprint author), Dalian Univ Technol, Sch Pharmaceut Sci & Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China..Li, Yueqing,Wang, Shisheng,Guo, Xiuhan,Wang, Liu,Zhao, Weijie.Total Synthesis of Two Pyrrole Spiroketal Alkaloids: Pollenopyrroside A and Capparisine B[J],SYNLETT,2015,26(7):921-926
Patents
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一类二氢卟吩半乳糖苷类化合物及其制备方法与应用
一类二氢卟吩葡萄糖苷类化合物及其制备方法与应用
具有光、声敏活性的二氢卟吩青蒿琥酯结合物及其制备方法与应用
亲水性长波长二氢卟吩类光、声敏剂及其制备方法与应用
一类生物亲和探针分子及其制备方法与应用
亲水性长波长二氢卟吩类光、声敏剂及其制备方法与应用
Published Books
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Research Projects
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冷链产品表面消毒检测与性能评估,地市厅局(含县)项目,2022-02-08,已提已提交结题报告
化学药品自动化消毒技术攻关项目,地市厅局(含县)项目,2022-02-08,在研
一类可用于活性化合物靶标蛋白研究的新型生物亲和探针的设计、合成与评价,省、市、自治区科技项目,辽宁省博士科研启动基金,2015-08-27,2023-09-13,结题
一类含硼酸基可逆辅助亲和基团的小分子探针的设计、合成与评价,国家自然科学基金项目,2015-08-18,结题
肿瘤低氧微环境选择性抗肿瘤活性化合物Furospinosulin-1的靶标蛋白发现用小分子探针的设计、合成与应用,主管部门科技项目,2015-03-02,2023-09-06,结题
具有可控配基密度的生物活性表面的构筑及功能研究,国家自然科学基金项目,2017-08-17,2022-04-18,结题