孔凡涛，博士，副教授。2014年毕业于日本 Kochi University of Technology (KUT) 获工学博士学位。2014-2017年在法国国家科学研究中心 (CNRS) 原子能与可替代新能源研究所 (CEA Cadarache) 从事博士后 (Postdoc) 研究。2018年工作于韩国浦项科技大学 (POSTECH) 任助理研究员 (Assistant Researcher)。2023年日本 Kochi University of Technology 客座研究员。

 

2019年，大连理工大学引进海外人才，大连市高层次人才。主持国家自然科学基金、辽宁省自然科学基金、大连理工大学引进人才科研启动项目、中央高校科研业务费理科基础研究、中央高校科研业务费交叉探索项目、教育部重点实验室开放课题基金等；参与国家自然科学基金重点项目、国家重点研发计划子课题等。研究方向围绕国家碳中和与绿色可再生能源的重大发展战略，主要从事微藻光合代谢工程及合成生物学的研究，利用微藻光合固碳助力碳中和及可持续绿色生物能源生产。近几年，代表性研究成果，以第一/通讯作者发表在 Plant Cell (IF: 12.10), New Phytologist (IF: 10.20), Plant Journal (IF: 7.01), Journal of Hazardous Materials (IF: 13.6), Journal of Agricultural and Food Chemistry (IF: 6.1), ACS Sustainable Chemistry & Engineering (IF: 8.4), Current Opinion in Biotechnology (IF: 7.7) 等专业领域国际著名TOP学术刊物上，申请发明专利5项，已授权2项。担任Frontiers in Plant Science (IF: 5.75), Frontiers in Marine Science (IF: 4.91), Discover Applied Sciences (IF: 2.3) 等杂志编委, Biotechnology for Biofuels, Journal of Cellular Physiology, Plant and Cell Physiology, Plant Cell Reports, BMC Plant Biology, Energy Advanced,GCB-Bioenergy, ACS Sustainable Chemistry & Engineering, Plant Journal, Journal of Experimental Botany 等国际杂志的审稿人。

指导本科生两次参加“国际遗传工程机器大赛 (iGEM)” 均获得金奖 (2019, 2021), 国家级大学生创新创业训练计划项目2项 (2020,2021)；全国大学生生命科学竞赛 (科学探究类) 二等奖2项 (2022, 2024)。辽宁省生命科学竞赛（创新创业类）一等奖 2项(2022, 2024) , 第九届辽宁省大学生创新创业年会 一等奖1项 (2024)、二等奖1项 (2022)。指导本科生（第一作者）完成的论文发表在 ACS Sustainable Chemistry & Engineering (IF: 8.4), Biotechnology and Bioengineering (IF: 4.56) 等杂志4篇。指导的研究生获得大连理工大学优秀毕业生（2024），优秀硕士论文 (2022, 2024)，目前招收生物学、生物工程、生物化工、生物与医药等全日制学术及专业型硕士。

欢迎对生物工程、生物科学及生命医药研究感兴趣的同学报考，期待你们的加盟！

E-mail：kongfantao@dlut.edu.cn

代表性SCI论文:

47. Dou X, Li M, Ge Y, Yin G, Wang X, Xue S, Jia B, Zi L, Wan H, Xi Y, Chi Z, Kong F* (2024). Photoproduction of aviation fuel β-caryophyllene from the eukaryotic green microalga Chlamydomonas reinhardtii. Biotechnology and Bioengineering (IF: 4.56, Accepted). (*通讯作者). 

46. Kong F*, Blot C, Liu K, Kim M, Li-Beisson Y (2024). Advances in algal lipid metabolism and their use to improve oil content. (2024, 87:103130). Current Opinion in Biotechnology  (IF: 8.9). (*通讯作者). 

45. Zhang H, Ma S, Dou X, Ru Chen R, Lu H, Chi Z, Xue S, Li-Beisson Y, Kong F* (2024). Harnessing algal peroxisomes for efficient poly-hydroxybutyrate (PHB) production. (2024,12(8):3312–3321) ACS Sustainable Chemistry & Engineering (IF: 8.4) (*通讯作者). 

44. Testi S; Kuhn M; Allasia V; Auroy P; Kong F; Peltier G; Pagnotta S; Cazareth J; Keller H; Panabières F. The Phytophthora parasitica effector AVH195 interacts with ATG8, attenuates host autophagy and promotes biotrophic infection. (2024, 22(1):100) BMC Biology (IF: 7.1). 

43. Wang X, Ma S, Kong F* (2024). Microalgae Biotechnology: Methods and Applications. （2024, 11, 965）Bioengineering (IF: 3.8) (*通讯作者). 

42. Xi Y, Han B, Meng Z, Li Y, Zeng X, Kong F*, You T, Bi R，Wang S, Jia Y (2024). Arsenic Uptake and Biotransformation Mechanisms in Dunaliella salina: Insights into Physiological and Molecular Responses. (2024, 80: 103539). Algal Research (IF: 5.72). (*通讯作者). 

41. Zhao J, Ge Y, Liu K,  Yamaoka Y, Zhang D, Chi Zh, Akkaya M, Kong F* (2023). Overexpression of a MYB1 Transcription Factor Enhances Triacylglycerol and Starch Accumulation and Biomass Production in the Green Microalga Chlamydomonas reinhardtii. (2023, 71(46):17833-17841). Journal of Agricultural and Food Chemistry (IF: 6.1) (*通讯作者).

40. Xi Y, Han B, Kong F*, You T, Bi R, Zeng X, Wang S, Jia Y (2023). Enhancement of Arsenic Uptake and Accumulation in Green Microalga Chlamydomonas reinhardtii through Heterologous Expression of the Phosphate Transporter DsPht1. (2023, 459, 132130). Journal of Hazardous Materials. (IF: 13.6) (*通讯作者).

39. Kong F*, Cao X and Schulz-Raffelt M (2023). Editorial: Metabolic Engineering for Bioresources and Bioenergies Production from Microalgae. (2023, 10:1114854). Frontiers in Bioengineering and Biotechnology. (IF: 6.064) (*通讯作者).

38. Zhang J, Wang J, Liu Y, Zhang Y, Wang J, Chi Z, Kong F（2023）.Microalgal-bacterial biofilms for wastewater treatment: Operations, performances, mechanisms, and uncertainties (2023，24:167974). Science of The Total Environment (IF: 9.8).

37. Chen R, Yamaoka Y, Feng Y, Chi Z, Xue S, Kong F* (2023).  Co-expression of Lipid Transporters Simultaneously Enhances Oil and Starch Accumulation in the Green Microalga Chlamydomonas reinhardtii under Nitrogen Starvation. (2023, 13(1), 115). Metabolites. (IF: 5.581) (*通讯作者).

36. Kong F*, Li M, Liu K, Ge Y, Yamasaki T, Beyly-Adriano A, Ohama T, Li-Beisson Y (2023). Efficient approaches for nuclear transgene stacking in the unicellular green microalga Chlamydomonas reinhardtii. (2023,71:103048). Algal Research (IF: 5.72). (*通讯作者).

35. Lu H, Liu K, Zhang H, Xie X, Ge Y, Chi Z, Xue S, Kong F*, Ohama T (2023). Enhanced triacyclglycerols and starch synthesis in Chlamydomonas stimulated by the engineered biodegradable nanoparticles (2023, 107(2-3):971-983). Applied Microbiology and Biotechnology (IF: 5.560) (*通讯作者).

34. Chen R, Yang M, Li M, Zhang H, Lu H, Dou X, Feng S, Xue S, Zhu C, Chi Z, Kong F* (2022). Enhanced accumulation of oil through co‑expression of fatty acid and ABC transporters in Chlamydomonas under standard growth conditions. (2022, 15(1):54 ). Biotechnology for Biofuels. (IF: 7.67) (*通讯作者).

33. Choi B, Shim D, Kong F, Auroy P, Lee Y, Li-Beisson Y, Lee Y, Yamaoka Y. The Chlamydomonas transcription factor MYB1 mediates lipid accumulation under nitrogen depletion (2022, 235(2):595-610.). New Phytologist (IF: 10.15).

32. Zhu C, Ji Y, Du X, Kong F, Chi Z, Zhao Y. A smart and precise mixing strategy for efficient and cost-effective microalgae production in open ponds. (2022). Science of The Total Environment, (IF: 7.963).

31. Al-Azab A, Aoki Y, Sarian F, Sori Y, Widyaningrum D, Yamasaki T, Kong F, Ohama T. Chronological transcriptome changes induced by exposure to cyanoacrylate resin nanoparticles in Chlamydomonas reinhardtii with a focus on ROS development and cell wall lysis-related genes. Algal Research (IF: 5.72) (2022, 68,102884).

30. Liu K , Chen R, Yang R, Chen Y, Zhu C, Tang Y, Kong F*. Genome editing approaches applied to microalgae-based fuels. 3rd Generation of Biofuels (Chapter 3), Woodhead Publishing, (2022). (*通讯作者).

29. Xi Y, Bian J, Luo G, Kong F*, Chi Z*. Enhanced β-carotene production in Dunaliella salina under relative high flashing light (2022, 67, 102857). Algal Research (IF: 5.72).  (*通讯作者).

28. Yang M, Xie X, Kong F, Xie K, Yu S, Ma J, Xue S*, Gong Z* (2022). Differences in Glycerolipid Response of Chlamydomonas reinhardtii Starchless Mutant to High Light and Nitrogen Deprivation Stress under Three Carbon Supply Regimes. (2022, 13:860966). Frontiers in Plant Science.  (IF: 5.75).

27. Zhang Y, Wang J, Zhang J, Chi Z, Kong F, Zhang Q. The long overlooked microalgal nitrous oxide emission: Characteristics, mechanisms, and influencing factors in microalgae-based wastewater treatment scenarios. Science of The Total Environment (IF: 7.963). 2022 ;856(Pt 2):159153.

26. Xi Y; Zhang J; Kong F*; Che J; Chi Z (2022). Kinetic Modeling and Process Analysis for Photo-Production of β-Carotene in Dunaliella salina. (2022, 9: 4). Bioresources and Bioprocessing (IF:  4.57) (*通讯作者).

25. Yu C, Pang H, Wang J, Chi Z, Zhang Q, Kong F, Xu Y, Li S, Che J (2022). Occurrence of antibiotics in waters, removal by microalgae-based systems, and their toxicological effects: A review. (2022, 813, 151891). Science of The Total Environment. (IF: 7.963). 

24. Li-Beisson Y, Kong F, Wang P, Lee Y, Kang B (2021). The disassembly of lipid droplets in Chlamydomonas. (2021, 231(4): 1359-1364). New Phytologist (IF: 10.15). 

23. Li B, Chen R, Zhu C, Kong F* (2021). Glowing Plants Can Light Up the Night Sky? A Review. (2021, 118(10): 3706-3715). Biotechnology and Bioengineering. (IF: 4.56) (*通讯作者). 

22. Xi Y, Kong F*, Chi Z (2021). ROS induce β-carotene biosynthesis caused by changes of photosynthesis efficiency and energy metabolism in Dunaliella salina under stress conditions. (2021 January; (8) 613768) Frontiers in Bioengineering and Biotechnology. (IF: 5.89) (*通讯作者).

21. Zhu C, Xi Y, Zhai X, Wang J, Kong F, Chi Z (2021).Pilot outdoor cultivation of an extreme alkalihalophilic Trebouxiophyte in a floating photobioreactor using bicarbonate as carbon source (2021 February 283; 124648) Journal of Cleaner Production (IF: 9.297).

20. Lee J, Yamaoka Y, Kong F, Cagnon C, Beyly-Adriano A, Jang S, Gao P, Kang B, Li-Beisson Y, Lee Y (2020). The phosphatidylethanolamine-binding protein DTH1 mediates degradation of lipid droplets in Chlamydomonas reinhardtii. (2020 September; 117 (37) 23131-23139) PNAS (IF: 11.20).

19. Jang S†, Kong F†, Lee J†, Choi B, Wang P, Gao P, Yamano T, Fukuzawa H, Kang B, Lee Y (2020). CrABCA2 Facilitates Triacylglycerol Accumulation in Chlamydomonas reinhardtii under Nitrogen Starvation. (†共同一作, 2020; 43(1): 48-57) Molecules and Cells. (IF: 5.03)

18. Zhu C, Che J, Zhai X, Wang J,Kong F, Chi Z (2020). Cost-effective and efficient production of carbohydrate from an alkalihalophilic Leptolyngbya sp. in a photobioreactor with periodical mixing.(2020, 8(40): 15310–15316) ACS Sustainable Chemistry & Engineering. (IF: 8.19)

17. Yang M, Kong F, Xie X, Wu P, Chu Y, Cao X, Xue S (2020). Galactolipid DGDG and Betaine Lipid DGTS Direct De Novo Synthesized Linolenate into Triacylglycerol in Stress-induced Starchless Mutant of Chlamydomonas reinhardtii.(2020; 61(4), 851–862) Plant & Cell Physiology. (IF: 4.93)

16. Zhu C, Zhai X, Xi Y,  Wang J, Kong F, Zhao Y, Chi Z (2020). Efficient CO2 Capture from the Air for High Microalgal Biomass Production by a Bicarbonate Pool. (2020, 37, 320-327) Journal of CO2 Utilization. (IF: 7.13)

15. Kong F*, Yamaoka Y, Ohama T, Lee Y, Li-Beisson Y (2019). Molecular Genetic Tools and Emerging Synthetic Biology Strategies to Increase Cellular Oil Content in Chlamydomonas reinhardtii. (2019 June; 60(6): 1184–1196) Plant & Cell Physiology. (IF: 4.93) (*通讯作者).

14. Romero IT,  Kong F, Légeret B, Beisson F, Peltier G, Li-Beisson Y (2020). Chlamydomonas cell cycle mutant crcdc5 over-accumulates starch and oil. (2020 February, 169, 54-61) Biochimie. (IF: 4.08)

13. Liang Y, Kong F, Romero IT, Burlacot A, Cuiné S, Légeret B, Billon E, Brotman Y, Alseekh S, Fernie A, Beisson F, Peltier G, Li-Beisson Y (2019). Branched-Chain Amino Acid Catabolism Impacts Triacylglycerol Homeostasis in Chlamydomonas reinhardtii. (2019 April;179(4):1502-1514) Plant Physiology. (IF: 8.34)

12. Kong F, Burlacot A, Liang Y, Légeret B, Alseekh S, Brotman Y, Fernie A, Krieger-Liszkay A, Beisson F, Peltier G, Li-Beisson Y (2018). Interorganelle Communication: Peroxisomal MALATE DEHYDROGENASE2 Connects Lipid Catabolism to Photosynthesis through Redox Coupling in Chlamydomonas. (2018 August; (30):1824–1847) Plant Cell. (IF: 11.28)

11. Zhai X#, Zhu C#, Zhang Y, Pang H, Kong F, Wang J, Chi Z (2020). Seawater supplemented with bicarbonate for efficient marine microalgae production in floating photobioreactor on ocean: a case study of Chlorella sp (2020 October; (738) 139439). Science of the Total Environment. #Co-first author. (IF: 7.96).

10. Yamaoka Y, Shin S, Choi B, Kim H, Jang S, Yamano T, Kajikawa M, Kong F, Légeret B, Li-Beisson Y, Fukuzawa H, Lee Y (2019). The bZIP1 Transcription Factor Regulates Lipid Remodeling and Contributes to ER Stress Management in Chlamydomonas reinhardtii. (2019 May;31(5):1127-1140) Plant Cell. (IF: 11.28)

9. Kong F, Romero IT, Warakanont J, Li-Beisson Y (2018). Lipid catabolism in microalgae. (2018 June; 218(4): 1340-1348) New Phytologist. (IF: 10.15)

8. Kong F*, Li-Beisson Y (2018). Identification of Insertion Site by RESDA-PCR in Chlamydomonas Mutants Generated by AphVIII Random Insertional Mutagenesis. (2018 February; (03)8:e2718) Bioprotocol. (*通讯作者). 

7. Kong F, Liang Y, Légeret B, Beyly-Adriano A, Blangy S, Haslam RP, Napier JA, Beisson F, Peltier G, Li-Beisson Y (2017). Chlamydomonas carries out fatty acid β-oxidation in ancestral peroxisomes using a bona fide acyl-CoA oxidase. (2017 April; 90(2):358-371) Plant Journal. (IF: 6.42)

6. Zhu C, Zhai X, Xi Y, Wang J, Kong F, Zhao Y, Chi Z (2019). Progress on the development of floating photobioreactor for microalgae cultivation and its application potential. (2019 Nov 21;35(12):190) World Journal of Microbiology and Biotechnology. (IF: 3.13)

5. Goold HD #, Nguyen HM #,Kong F, Beyly-Adriano A, Légeret B, Billon E, Cuiné S, Beisson F, Peltier G, Li-Beisson Y (2016). Whole genome re-sequencing identifies a quantitative trait locus repressing carbon reserve accumulation during optimal growth in Chlamydomonas reinhardtii. (2016 May; 6:25209) Scientific Report. #Co-first author. (IF: 4.38)

4. Kurniasih SD, Yamasaki T, Kong F, Okada S, Widyaningrum D and Ohama T (2016). UV-mediated Chlamydomonas mutants with enhanced nuclear transgene expression by disruption of DNA methylation-dependent and independent silencing systems. (2016 December; 92 (6): 629-641) Plant Molecular Biology. (IF: 4.08)

3. Kong F, Yamasaki T, Kurniasih SD, Hou L, Li X, Ivanova N, Okada S, Ohama T (2015). Robust expression of heterologous genes by selection marker fusion system in improved Chlamydomonas strains. (2015 Sep; 120(3):239-245) Journal of Bioscience and Bioengineering. (IF: 3.18)

2. Kong F, Yamasaki T and Ohama T (2014). Expression levels of domestic cDNA cassettes integrated in the nuclear genomes of various Chlamydomonas reinhardtii strains. (2014 May;117(5):613-616) Journal of Bioscience and Bioengineering. (IF: 3.18)

1. Hou L, Wang P, Kong F, Park H, Kobiro K, Ohama T (2013). Mesoporous TiO2 nanoparticles: a new material for biolistic bombardment. (2013 January; 61(1):58-60) Phycological Research. (IF: 1.67)

已授权发明专利：
1. 孔凡涛；陈如；鲁晗；张昊。一种正常培养条件下高产油及淀粉的工程藻及其构建方法与应用。申请日期：2022-01-27, 授权日期：2024年02月13日 ，专利号：ZL202210103186.8

2. 贾永锋; 韩博蕾; 席一梅; 孔凡涛; 王少锋; 曾祥峰。一种正常培养条件下高产油及淀粉的工程藻及其构建方法与应用。申请日期：2022-11-08, 授权日期：2024年05月24日 ，专利号：ZL 202211394454.2

2. Ohama T, (*), Yamasaki T, Park H-S, Kong F, Hou L, ボツリオコッカスブラウニーの単細胞単離方法及び単細胞培養方法。授权日期： 2013.8.22, 授予国家：日本，专利号：WO2013121509 A1

获得的荣誉与奖励：

2024  辽宁省细胞生物学会理事

2023  大连理工大学校教学质量优良奖

2023  大连理工大学基本科研业务费优秀本科生基础研究专项，指导教师

2023  第九届中国国际“互联网+”大学生创新创业大赛 三等奖，指导教师

2022  全国大学生生命科学竞赛 (科学探究类) 二等奖，指导教师

2022  辽宁省大学生生命科学竞赛 (创新创业类) 一等奖，指导教师

2022  大连理工大学优秀硕士学位论文，指导教师

2022  第九届辽宁省大学生创新创业年会 (学术论文) 二等奖，指导教师

2021  辽宁省首届普通高等学校教师教学大赛，三等奖，辽宁省教育厅

2021  荣获2021年校教学质量优良奖，大连理工大学

2021  美国国际遗传工程机器大赛（iGEM）金奖，指导教师

2021  第四届大连理工大学 iGEM-DUT校内选拔赛，一等奖，指导教师

2021  辽宁省新引进人才奖励，海外留学归来博士，辽宁省人社厅

2020  教师讲课竞赛，一等奖，大连理工大学 生物工程学院

2019  美国国际遗传工程机器大赛（iGEM）金奖，指导教师

2019  青年科技工作者国际和港澳台学术交流资助项目第八批资助, 辽宁省科协

2019  青年教师讲课竞赛，三等奖，大连理工大学

2019  青年教师讲课竞赛，二等奖，大连理工大学 生物工程学院

2018  韩国全球前沿技术支持计划ICT项目 Researcher fellowship

2014  法国国家科学研究中心 (CNRS) Postdoc fellowship

2013  日本 Kochi University of Technology (KUT) 学术研究奖励赏

2012  中国优秀留学生学友会会长，中国教育部驻日本大使馆

     主持（或参与）的主要科研项目：

国家自然科学基金 (青年项目)，主持

辽宁省自然科学基金 (面上项目)，主持

中央高校基本科研业务费 (引进人才项目)，主持

中央高校基本科研业务费 (理科基础研究项目)，主持

中央高校基本科研业务费 (交叉探索项目)，主持

教育部重点实验室课题经费 (交叉探索项目)，主持

国家重点研发计划（课题项目；科技部), 参与

国家自然科学基金重点项目（国家自然基金委), 参与

大连市科技重大专项（课题项目；大连市), 参与

法国国家重点研发计划（MUsCA项目；ANR), 参与

韩国全球前沿技术支持计划 (ICT项目，NRFR), 参与

日本创新性前沿科学技术重点研究项目 (CREST项目, JST), 参与

指导本科生（第一作者）发表论文：

4. Zhang H^#, Ma S^# (本科生), Dou X, Ru Chen R, Lu H, Chi Z, Xue S, Li-Beisson Y, Kong F* (2024). Harnessing algal peroxisomes for efficient poly-hydroxybutyrate (PHB) production. (2024, 12(8):3312–3321) ACS Sustainable Chemistry & Engineering (IF: 8.4) (^#共同一作)(*通讯作者). 

3. Li B (本科生), Chen R, Zhu C, Kong F* (2021). Glowing Plants Can Light Up the Night Sky? A Review. (2021, 118(10): 3706-3715). Biotechnology and Bioengineering. (IF: 4.56) (*通讯作者). 

2. Liu K（本科生） , Chen R, Yang R, Chen Y, Zhu C, Tang Y, Kong F*. Genome editing approaches applied to microalgae-based fuels. 3rd Generation of Biofuels (Chapter 3), Woodhead Publishing, (2022). (*通讯作者). 

1. 刘原源 (本科生)，曾威阳，陈如，葛云龙，孜力汗，杨君，孔凡涛*。微藻趋向运动及其靶向运输应用研究进展. (2022, 38(2): 578-591),《生物工程学报》(*通讯作者)。

学术社会兼职

SN Applied Sciences (Discover Applied Sciences) (2024-  ), Associate Editor

Advanced Biotechnology (2023-  ), Editorial Borad

Frontiers in Marine Science (2021-  ), Editorial Borad

Frontiers in Plant Science (2021-  ), Editorial Borad

Modern Agriculture and Biotechnology (2021-  ), Editorial Borad

Journal of Plant Sciences (2020-  ), Editor

The Open Microalgae Biotechnology (2019-  ), Associate Editor

Reviewers: Plant Journal, Journal of Experimental Botany, Biotechnology for Biofuels, Frontier in Plant Science, Plant and Cell Physiology, Journal of Cellular Physiology, Applied Microbiology and Biotechnology, Journal of Applied Phycology, Scientific Reports, ACS Sustainable Chemistry & Engineering, Peer J, PLoS One, Biomass Conversion and Biorefinery, Journal of Applied Microbiology, Plant Cell Reports, Algal Research,GCB-Bioenergy, Heliyon,Bioresources and Bioprocessing, BMC Plant Biology, Journal of Applied Phycology, Molecular Biology Reports, Advanced Biotechnology, Green Carbon，Frontiers in Microbiology，International Journal of Molecular Sciences, RSC Energy Advanced, ACS Applied Polymer Materials, Energy Advanced,  et al.