Wang Weiqiang
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冠脉支架系统瞬时膨胀过程的有限元分析及其优化设计
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Indexed by:期刊论文

Date of Publication:2005-06-30

Journal:中国生物医学工程学报

Included Journals:Scopus、EI、PKU、ISTIC、CSCD

Volume:24

Issue:3

Page Number:313-318,329

ISSN No.:0258-8021

Key Words:支架;再狭窄;有限元分析/有限元方法;优化设计

Abstract:经皮穿刺冠脉支架技术已成为治疗冠心病的有效手段,在实践该技术过程中,球囊与支架的配套情况和支架的设计影响着支架瞬时膨胀的效果,球囊/支架系统在病变处的瞬时非均匀膨胀,即Dogboning现象,是造成支架端部急性动脉损伤的主要原因之一.这种损伤与支架内再狭窄(in-stent restenosis)有着密切的联系.为减少这种损伤,降低支架植入再狭窄率.本研究利用有限元技术对六组不同搭配的球囊/支架系统的瞬时膨胀情况进行了对比分析.结果表明,在球囊、支架的搭配中,减小球囊有效长度的过盈量和增加支架端部支撑体的筋宽,这两种方法共同作用,可以有效抑制球囊/支架系统在瞬时膨胀过程中的Dogboning现象.验证实验与模拟结果比较吻合,说明有限元法可以胜任球囊/支架的优化设计工作.

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Associate Professor
Supervisor of Doctorate Candidates
Supervisor of Master's Candidates

Gender:Male

Alma Mater:Dalian University of Technology

Degree:Doctoral Degree

School/Department:School of Materials Science & Engineering

Discipline:Materials Science. Biomedical Engineering

Business Address:Room 224
School of Materials Science and Engineering,
Dalian University of Technology,
Liaoning 116024,
P. R. of China

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