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个人信息Personal Information
教授
博士生导师
硕士生导师
主要任职：Director, State Key laboratory of Fine Chemicals
其他任职：精细化工国家重点实验室主任、国务院学科评议组成员
性别：男
毕业院校：大连理工大学
学位：博士
所在单位：化工学院
学科：应用化学. 精细化工. 化学生物学
办公地点：大连理工大学精细化工国家重点实验室
西部校区化工实验楼F-202#
http://peng-group.dlut.edu.cn/
联系方式：大连理工大学精细化工国家重点实验室 西部校区化工实验楼F-202 辽宁省大连市高新区凌工路2号，大连116024 Tel: 0411-84986306; Fax: 0411-84986292；课题组网址：http://peng-group.dlut.edu.cn/
电子邮箱：pengxj@dlut.edu.cn
A fluorescein derivative-based fluorescent sensor for selective recognition of copper(II) ions
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论文类型：期刊论文
发表时间：2018-03-15
发表刊物：JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
收录刊物：SCIE
卷号：355
期号：,SI
页面范围：67-71
ISSN号：1010-6030
关键字：Fluorescent sensor; Fluorescein derivative; copper(II) ions
摘要：A novel fluorescein-based sensor FR-L was designed and synthesized with good yield for recognizing copper(II) ions in living cells. The sensor, incorporating 5-aminoisophthalic acid methyl ester with fluorescein, was synthesized and fully characterized by crystal test, (HNMR)-H-1, and ESI-MS analyses. The sensor showed a quenching response with the addition of copper(ll) ions which was ascribed to the cooperation between the sensor and copper(II) ions. Meanwhile, the sensor exhibited high selectivity over other metal ions and displayed more obvious changes of absorption. Finally, fluorescent imaging in living cells indicated the capability of detecting copper(II) ions in biological system. (C) 2017 Published by Elsevier B.V.