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个人信息Personal Information
教授
博士生导师
硕士生导师
主要任职：Director, State Key laboratory of Fine Chemicals
其他任职：精细化工国家重点实验室主任、国务院学科评议组成员
性别：男
毕业院校：大连理工大学
学位：博士
所在单位：化工学院
学科：应用化学. 精细化工. 化学生物学
办公地点：大连理工大学精细化工国家重点实验室
西部校区化工实验楼F-202#
http://peng-group.dlut.edu.cn/
联系方式：大连理工大学精细化工国家重点实验室 西部校区化工实验楼F-202 辽宁省大连市高新区凌工路2号，大连116024 Tel: 0411-84986306; Fax: 0411-84986292；课题组网址：http://peng-group.dlut.edu.cn/
电子邮箱：pengxj@dlut.edu.cn
Imaging dichromate in living cells with a fluorescence probe
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论文类型：期刊论文
发表时间：2018-03-15
发表刊物：JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
收录刊物：SCIE
卷号：355
期号：,SI
页面范围：165-174
ISSN号：1010-6030
关键字：Dichromate chemosensor; Rhodamine derivatives; Determination of Cr2O72- in water
摘要：The dichromate as an industrial oxidant has a very extensive application. However, as one of the heavy metal elements, chromium has become a great threat to the organism and environment due to its carcinogenicity and mutageicity. So far, there is only a small number of detection and imaging methods for dichromate. In this work, a new fluorescent probe RhoCr for detecting dichromate based on in situ Cr3+-controlled opening of spirolactam-ring in a rhodamine dye after Cr2O72- reduced to Cr3+ by NaHSO3 in solution and self-reduction in organism is reported, which displays a strong enhancement of fluorescence emission (lambda(em) 582 nm), fast response (completed within 2 min) and excellent sensitivity (DL 1.18 nM). RhoCr successfully obtained fluorescence images of the intracellular Cr2O72-. In addition, the effect have been exhibited in tap water and pool water, which will be crucial to the detection of dichromate in the environment. (C) 2017 Elsevier B.V. All rights reserved.