Release Time:2019-03-11  Hits:

Indexed by: Journal Article

Date of Publication: 2011-11-01

Journal: Gongneng Cailiao/Journal of Functional Materials

Included Journals: Scopus、ISTIC、PKU、EI

Volume: 42

Issue: SUPPL. 5

Page Number: 912-915+919

ISSN: 10019731

Abstract: Fe 3O 4 nanoparticles prepared by coprecipitation method were surface functionalized with the silane coupling agent of 3-methacryloylpropyl trimethoxysilane (MPS), then the MPS on the surface of Fe 3O 4 nanoparticles was copolymerized with the quaternary ammonium salt monomers (quaternization of dimethylaminoethyl methacrylate with benzyl bromide or bromohexane) by free radical polymerization, and the recyclable antibacterial polycation grafted Fe 3O 4 magnetic nanoparticles (pQAC-Fe 3O 4) were obtained. The morphology and surface composition of nanoparticles was characterized by XRD, FT-IR, DLS, TEM and TGA. It was found that pQAC-Fe 3O 4 nanoparticles showed a wide spectrum of excellent antibacterial activity in vitro by the colony count method. The antimicrobial activity of the magnetic pQAC-Fe 3O 4 nanoparticles which exhibited a response to an external magnetic field could retain 95% biocidal efficiency against E. coli after 10 cycles of repeated test. With the difference of two kinds of pQAC-Fe 3O 4, high antibacterial efficiency was attributed to not only the quaternary group density but also the substituent chain of the quaternary group.