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A fluorescent probe for H2S in vivo with fast response and high sensitivity

Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2015-11-21

Journal: CHEMICAL COMMUNICATIONS

Included Journals: Scopus、PubMed、SCIE

Volume: 51

Issue: 90

Page Number: 16225-16228

ISSN: 1359-7345

Abstract: In this work, we design and synthesize a new near-infrared (NIR) ratiometric fluorescent probe FD-H2S for the highly sensitive (DL 68.2 nM) detection of H2S with fast response (15 s), large emission shift (220 nm) and excellent enhancement (168-fold in ratiometric value). The probe could be applied for monitoring and imaging of exogenous or endogenous H2S in live MCF-7 cells and in live mice with the fastest response.

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