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A fluorescent probe for H2S in vivo with fast response and high sensitivity

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Indexed by:期刊论文

Date of Publication:2015-11-21

Journal:CHEMICAL COMMUNICATIONS

Included Journals:SCIE、PubMed、Scopus

Volume:51

Issue:90

Page Number:16225-16228

ISSN No.:1359-7345

Abstract:In this work, we design and synthesize a new near-infrared (NIR) ratiometric fluorescent probe FD-H2S for the highly sensitive (DL 68.2 nM) detection of H2S with fast response (15 s), large emission shift (220 nm) and excellent enhancement (168-fold in ratiometric value). The probe could be applied for monitoring and imaging of exogenous or endogenous H2S in live MCF-7 cells and in live mice with the fastest response.

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