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Indexed by:期刊论文

Date of Publication:2015-01-14

Journal:CHEMICAL COMMUNICATIONS

Included Journals:SCIE、PubMed、Scopus

Volume:51

Issue:4

Page Number:792-795

ISSN No.:1359-7345

Abstract:The first Golgi-localized cyclooxygenase-2 (COX-2)-specific near-infrared (NIR) fluorescent probe, Niblue-C6-IMC, able to detect cancer cells, was designed. Importantly, Niblue-C6-IMC preferentially labeled the tumors in a mouse tumor model with deep tissue penetration capacity. It may be a promising molecular tool for guiding tumor resection during surgery.