Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2015-01-14

Journal: CHEMICAL COMMUNICATIONS

Included Journals: Scopus、PubMed、SCIE

Volume: 51

Issue: 4

Page Number: 792-795

ISSN: 1359-7345

Abstract: The first Golgi-localized cyclooxygenase-2 (COX-2)-specific near-infrared (NIR) fluorescent probe, Niblue-C6-IMC, able to detect cancer cells, was designed. Importantly, Niblue-C6-IMC preferentially labeled the tumors in a mouse tumor model with deep tissue penetration capacity. It may be a promising molecular tool for guiding tumor resection during surgery.