Hits:

Indexed by:期刊论文

Date of Publication:2014-07-01

Journal:SCIENCE CHINA-CHEMISTRY

Included Journals:SCIE、EI

Volume:57

Issue:7

Page Number:1043-1047

ISSN No.:1674-7291

Key Words:turn-on; gold ion fluorescent probe; low detection limit; good selectivity and sensitivity; bioimaging application

Abstract:A new fluorescent probe RY was synthesized for the detection of Au3+ ions based on a rhodamine B derivative. The fluorescent probe showed good selectivity and sensitivity to Au3+ ions. Obvious color and fluorescence changes could be observed with the naked eye while the fluorescent probe reacted with the Au3+ ions. The detection limit of the probe was determined to be 36 ppb by the fluorescence titration; the excellent linear relationship suggests that the probe is potentially useful for quantitative detection of Au3+ in vitro. We also demonstrated its bioimaging application in both living cells and mice; this was the first time that a fluorescent probe was successfully applied to imaging Au3+ in living animals.