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Indexed by:期刊论文

Date of Publication:2011-04-26

Journal:ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Included Journals:Scopus、SCIE、EI、PubMed

Volume:50

Issue:18

Page Number:4180-4183

ISSN No.:1433-7851

Key Words:cell cycle; DNA; fluorescent probes; imaging agents; nucleus staining

Abstract:Seeing red: DEAB-TO-3 shows a large fluorescence enhancement upon binding to native DNA and a distinct selectivity for double-stranded DNA over total RNA. As a red fluorescent live-cell-permeant DNA minor groove binder, DEAB-TO-3 is promising for highly sensitive DNA detection in vitro and nucleus-specific imaging and DNA quantification in vivo (see picture). Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.