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性别: 男

毕业院校: 北京邮电大学

学位: 博士

所在单位: 控制科学与工程学院

学科: 微电子学与固体电子学. 光学工程

电子邮箱: huihuang@dlut.edu.cn

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A compact photometer based on metal-waveguide-capillary: application to detecting glucose of nanomolar concentration

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论文类型: 期刊论文

发表时间: 2015-05-28

发表刊物: SCIENTIFIC REPORTS

收录刊物: SCIE、PubMed、Scopus

卷号: 5

页面范围: 10476

ISSN号: 2045-2322

摘要: Trace analysis of liquid samples has wide applications in life science and environmental monitor. In this paper, a compact and low-cost photometer based on metal-waveguide-capillary (MWC) was developed for ultra-sensitive absorbance detection. The optical-path can be greatly enhanced and much longer than the physical length of MWC, because the light scattered by the rippled and smooth metal sidewall can be confined inside the capillary regardless of the incident-angle. For the photometer with a 7 cm long MWC, the detection limit is improved similar to 3000 fold compared with that of commercial spectrophotometer with 1 cm-cuvette, owing to the novel nonlinear optical-path enhancement as well as fast sample switching, and detecting glucose of a concentration as low as 5.12 nM was realized with conventional chromogenic reagent.

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