Hits:

Indexed by:期刊论文

Date of Publication:2013-05-01

Journal:CHEMISTRY-A EUROPEAN JOURNAL

Included Journals:SCIE、EI、PubMed、Scopus

Volume:19

Issue:21

Page Number:6538-6545

ISSN No.:0947-6539

Key Words:colorimetric analysis; fluorescence; fluorescent probes; mitochondria; thiol probes; imaging

Abstract:Born to dye: Five fluorescein analogues were synthesised (see scheme). One analogue was found to emit in the NIR region with a high quantum yield, excellent photostability and good permeability. Three derivatives were found to specifically stain mitochondria and one dye responds to thiols with a strong turn-on NIR fluorescence signal and colorimetric change, in vitro and in vivo.Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.