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个人信息Personal Information
副教授
博士生导师
硕士生导师
性别:男
毕业院校:浙江大学
学位:博士
所在单位:化工学院
学科:应用化学. 精细化工. 有机化学
办公地点:大连市甘井子区凌工路2号
大连理工大学西部校区E座406室
联系方式:15040537236 zhangtiexin@dlut.edu.cn
电子邮箱:zhangtiexin@dlut.edu.cn
Highly shape- and regio-selective peroxy-trifluoromethylation of styrene by metal-organic framework Cu-3(BTC)(2)
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论文类型:期刊论文
发表时间:2017-12-21
发表刊物:CATALYSIS SCIENCE & TECHNOLOGY
收录刊物:SCIE、EI
卷号:7
期号:4
页面范围:5872-5881
ISSN号:2044-4753
摘要:The peroxy and trifluoromethyl groups play important roles in pharmacy, but it is challenging to introduce both of them selectively into the target molecules in a homogeneous catalytic system. In the presence of the easily available metal-organic framework Cu-3(BTC)(2) (also well known as HKUST-1), novel peroxy-trifluoromethylation of styrenes was achieved in a heterogeneous mode. The rigid 3D framework of Cu-3(BTC)(2) is necessary to maintain the structural integrity of the binuclear paddle-wheel Cu(II) catalytic center for the effective electrophilic activation of Togni's reagent and TBHP with a low loading amount of the catalyst and its easy re-use, and the bowl bottom-like confined environment around the copper node is vital for the discrimination of reaction sites with different steric demands. Compared with homogeneous copper salts, the heterogeneous Cu-3(BTC)(2) showed superior catalytic activity and intrinsic shape- and regio-selectivity for this reaction. The peroxy moieties of the products could be easily converted to carbonyl or hydroxyl groups for further applications.
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