Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2013-05-01

Journal: CHEMISTRY-A EUROPEAN JOURNAL

Included Journals: Scopus、PubMed、EI、SCIE

Volume: 19

Issue: 21

Page Number: 6538-6545

ISSN: 0947-6539

Key Words: colorimetric analysis; fluorescence; fluorescent probes; mitochondria; thiol probes; imaging

Abstract: Born to dye: Five fluorescein analogues were synthesised (see scheme). One analogue was found to emit in the NIR region with a high quantum yield, excellent photostability and good permeability. Three derivatives were found to specifically stain mitochondria and one dye responds to thiols with a strong turn-on NIR fluorescence signal and colorimetric change, in vitro and in vivo.Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.