Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2013-01-28

Journal: ORGANIC & BIOMOLECULAR CHEMISTRY

Included Journals: Scopus、PubMed、EI、SCIE

Volume: 11

Issue: 4

Page Number: 555-558

ISSN: 1477-0520

Abstract: A BODIPY-based dye, OBEP, has been developed to act as a mitochondrial fluorescence probe. This dye is of high stability, low toxicity and insensitive in a pH range as wide as pH 2-10. Its uptake into mitochondria is independent of mitochondrial membrane potential in living cells. OBEP can label swollen mitochondria resulting from different degrees of cell damage in light and resist fading even after 12 h of incubation.