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发布时间：2019-03-09

论文类型：期刊论文

发表时间：2014-12-29

发表刊物：OPTICS EXPRESS

收录刊物：Scopus、SCIE

卷号：22

期号：26

页面范围：31977-31983

ISSN号：1094-4087

摘要：An all glass optofludic biosensor with high quality-factor FabryPerot cavity (FPC) channel was reported. The all glass sandwich structure can completely eliminate the etching roughness of the channel surface, and can extend the operating wavelength to visible and ultraviolet regions compared with that of Si-based sensor. The quality-factor of the FPC channel is 875, and the system noise can be reduced to 1.2 nV by combining optical differential detection with phase lock-in detection. A detection limit of 15ng/mL for glucose solution, which corresponds to a refractive index unit of 2.0 x 10(-9), was experimentally demonstrated. The all glass FPC sensor features low cost and robust compared with surface-plasmon-resonance sensor and ring-resonator sensor. (C) 2014 Optical Society of America