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Boc-L-甲基苯丙氨酸的合成与拆分

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Indexed by:期刊论文

Date of Publication:2008-07-10

Journal:高等学校化学学报

Included Journals:SCIE、PKU、ISTIC、CSCD

Volume:29

Issue:7

Page Number:1363-1366

ISSN No.:0251-0790

Key Words:非天然氨基酸;Boc-L-甲基苯丙氨;拆分

Abstract:利用Boc-2-氨基丙二酸二乙酯和甲基苄溴为原料,合成邻位、间位、对位甲基取代的Boc-苯丙氨酸乙酯,经枯草杆菌蛋白酶拆分得到对应的Boc-L-甲基苯丙氨酸.通过红外光谱、核磁共振、质谱及旋光度分析对3种物质的结构进行了表征.

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